Ophelia and Stefan

The relationship between cured vampire/human Stefan Salvatore and fairy/doppelgänger Ophelia Meade is a complicated, powerful romantic pairing, and a significant relationship in the series.

Stefan and Ophelia met when they were children and fell in love with each other. They didn't end up with each other because of the appearance of Katherine Pierce in 1864 and Stefan's death.

Ophelia ended up happily married with children which ultimately led to Christine Meade being born.

They are known to each other as "the one who got away."

They are known as "Stefelia".

Overview
Stefan and Ophelia fell in love with each other sometime during their childhood and even started a courtship with each other in 1857 when they were ten years old. Their parents approved of the pairing.

Their courtship started declining in 1864 after the appearance of Katherine Pierce. Ophelia was jealous of Stefan's seemingly developed feelings for Katherine and was worried about Katherine's relationship with both Salvatore Brothers.

After a while, Christine decided to let Stefan and Katherine have their relationship, deciding that she just wanted Stefan to be happy no matter who it was with.

Ophelia was devastated by Stefan and Damon's deaths at the hand of their father and seemingly lost contact with the Salvatore Family.

She then married someone else and had children which eventually led to her ancestor, Christine Meade, being born.